2-AZETIDINONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION,申请号WO1984JP00215-传众专利搜索

2-AZETIDINONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION

申请公布号：WO8504876(A1)

申请号：WO1984JP00215

申请日期：1984.04.24

申请公布日期：1985.11.07

申请人：

TAKEDA CHEMICAL INDUSTRIES, LTD.

发明人：KISHIMOTO, SHOJI;SENDAI, MICHIYUKI;OCHIAI, MICHIHIKO

分类号：C07D205/085;C07D209/48;C07D403/12;C07D417/12;(IPC1-7):C07D205/08

主分类号：C07D205/085

摘要：<p>2-Azetidinone derivatives having a group of formula (I), (wherein R<1> and R<2> may be the same or different and each represents hydrogen, alkyl, optionally substituted aryl or arylalkyl) in position 1 and an optionally acylated or protected amino group in position 3, salts thereof, and processes for their preparation comprising: (1) subjecting a 2-azetidinone derivatives having a group of formula (I), (wherein R<1> and R<2> are as defined above) in position 1 and an amino group in position 3 to the acylation or protective group-introducing reaction; or (2) reacting a 2-azetidinone derivative having a hydroxy group in position 1 and an optionally acylated or protected amino group in position 3 or its salt with a group of formula (II), (wherein W represents halogen, and R<1> and R<2> are as defined above) or its salt. The purpose compounds are utilized as antibacterial substances or the useful intermediates thereof.</p>