Phosphoric acid esters, their preparation and their use for the preparation of biocompatible surfaces.
申请公布号:EP0157469(A1)
申请号:EP19850300356
申请日期:1985.01.18
申请公布日期:1985.10.09
发明人:CHAPMAN, DENNIS;DURRANI, AZIZ AHMED
分类号:C07F9/09;A61L26/00;A61L33/00;C07C43/315;C07F5/00;C07F9/14;C07F9/6584;(IPC1-7):C07F9/10;C07F9/15;C08J7/12;A61L27/00;C07F9/02;C07F9/65
主分类号:C07F9/09
摘要:<p>A compound of formula <Chemistry id="chema01" num="0001"><Image id="ia01" he="20" wi="50" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>in which X<Sup>1</Sup> is a reactive group that can react to form a covalent bond with a reactive group on the surface of a material to be rendered biocompatible, X<Sup>2</Sup> is a group -O<Sup>e</Sup> or a precursor of such a group, n is 2, 3 or 4, Y is a group -*NR<Sub>3</Sub>A<Sup>e</Sup> wherein each R, which may be the same or different, is a C<Sub>1</Sub>-C<Sub>4</Sub> alkyl group and A<Sup>e</Sup> is an anion present when X<Sup>2</Sup> is an electrically neutral group or Y is <Chemistry id="chema02" num="0002"><Image id="ia02" he="10" wi="7" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein R<Sup>1</Sup> together with X<Sup>2</Sup> forms a direct bond between the nitrogen and the phosphorus atoms.</p>
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