FOERFARANDE FOER FRAMSTAELLNING AV 1-(HYDROXIMETYL)-1,6,7,11B-TETRAHYDRO-2H,4H/1,3/-OXAZINO- ELLER TIAZINO/4,3-A/ISOKINOLIN-DERIVAT.,申请号FI19850001155-传众专利搜索

FOERFARANDE FOER FRAMSTAELLNING AV 1-(HYDROXIMETYL)-1,6,7,11B-TETRAHYDRO-2H,4H/1,3/-OXAZINO- ELLER TIAZINO/4,3-A/ISOKINOLIN-DERIVAT.

申请公布号：FI851155(L)

申请号：FI19850001155

申请日期：1985.03.22

申请公布日期：1985.09.24

申请人：

RICHTER GEDEON VEGYESZETI GYAR R.T.

发明人：BERNATH, GABOR;KOBOR, JENOE;KALMAN, ALAJOS;FUELOEP, FERENC;SOHAJDA, ATTILA;EZER, ELEMER;HAJOS, GYOERGY;PALOSI, EVA;DENES, LASZLO;SPORNY, LASZLO

分类号：A61K31/535;A61K31/54;A61P1/12;A61P9/08;A61P25/08;C07D498/04;C07D513/04

主分类号：A61K31/535

摘要：The invention relates to 1-(hydroxymethyl)-1,6,7,11b-tetrahydro-2H,4H-[1,3]oxazino- or -thiazino-[4,3-a]isoquinoline derivatives of the formula (I), <IMAGE> (I) wherein R1 and R2 are alkoxy having from 1 to 6 carbon atoms, X is oxygen or sulfur, Y is =O, =S or an =NR3 group, wherein R3 is hydrogen, alkyl having from 1 to 6 carbon atoms, cycloalkyl having from 3 to 8 carbon atoms or optionally substituted phenyl, and acid addition and quaternary salts thereof.