ISOQUINOLINE COMPOUND

申请公布号：ZA8308237(B)

申请号：ZA19830008237

申请日期：1983.11.04

申请公布日期：1984.11.28

申请人：

GLAXO GROUP LIMITED

发明人：STANLEY FREDERICK DYKE;GORDON HANLEY PHILLIPPS

分类号：A61K31/47;A61P35/00;C07D471/04

主分类号：A61K31/47

摘要：5,14-Dihydrobenz[5,6]isoindolo[2,1-b]isoquinoline-8,13-dione <IMAGE> (I) exhibits anticancer activity. The compound can be prepared by reaction of 2-formyl-3-carboxyl-1,2,3,4-tetrahydroisoquinoline with 1,4-naphthoquinone and is particularly suitably administered parenterally in microcrystalline suspension form.

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