FOERFARANDE FOER FRAMSTAELLNING AV NYA BENSOFENONER.,申请号FI19840002389-传众专利搜索

FOERFARANDE FOER FRAMSTAELLNING AV NYA BENSOFENONER.

申请公布号：FI842389(A0)

申请号：FI19840002389

申请日期：1984.06.13

申请公布日期：1984.06.13

申请人：

CIBA-GEIGY AG

发明人：HAAS, GEORGES;VON SPRECHER, ANDREAS;FERRINI, PIER GIORGIO

分类号：C07C69/035;A61K31/165;A61K31/19;A61K31/195;A61K31/215;A61P29/00;C07C33/34;C07C45/67;C07C51/00;C07C59/90;C07C62/38;C07C65/40;C07C67/00;C07C69/753;C07C69/757;C07C69/76;C07C69/94;C07C201/00;C07C205/55;C07C231/00;C07C231/12;C07C231/14;C07C233/00;C07C235/82;C07C253/00;C07C255/40;C07C255/57;C07C313/00;C07C323/62;(IPC1-7):C07C/

主分类号：C07C69/035

摘要：<p>Substituted benzophenones of the formula <IMAGE> (I) in which Ph represents unsubstituted or substituted phenyl and R represents free, esterified or amidated carboxy, have anti-inflammatory and/or analgesic properties and can be used as active ingredients in medicaments. They are manufactured, for example, as follows: a compound or a mixture of compounds of the formula <IMAGE> (II) in which X1 and X2 together represent a group of the formula -C(=O)-O that is bonded via the carbonyl group to the radical Ph and X3 represents hydrogen, or one of the radicals X1 and X3 represents a group of the formula -C(=O)-Z, the other represents hydrogen and X2 represents a group R'O- in which R' represents hydrogen or a hydroxy-protecting group, is subjected to acid treatment and the primary product is decomposed solvolytically.</p>