Biocidal bromo:acyl-urea derivs. e.g. bromo:acetyl-urea, prodn. - by reacting a urea with bromo:acyl bromide using excess urea as acid binding agent,申请号DE19772720161-传众专利搜索

Biocidal bromo:acyl-urea derivs. e.g. bromo:acetyl-urea, prodn. - by reacting a urea with bromo:acyl bromide using excess urea as acid binding agent

申请公布号：DE2720161(A1)

申请号：DE19772720161

申请日期：1977.05.05

申请公布日期：1978.11.16

申请人：

CHEMISCHE FABRIK KALK GMBH

发明人：JENKNER,HERBERT,DR.;STRANG,ROBERT;NEISEN,GERTRUD

分类号：C07C273/18;C07C275/50;(IPC1-7):C07C127/22;A01N9/20

主分类号：C07C273/18

摘要：<p>In the prodn. of bromoacyl-urea derivs. of formula R-CH Br-CO-NH-CO-NH-R1 (I) (where R and R1 are H or alkyl) by reacting H2N-CO-NH-R1 (II) with Br-CHR-CO-Br (III) in the presence of an inert solvent and HBr-acceptors, an excess of (II) is used as the HBr-acceptor. (II) is pref. used in an amount of 2-3 (eps. 2) mol. per mol. (III). The pref. inert solvent is methyl acetate or ethyl acetate. Reaction temp. is generally 10-120 degrees C esp. 50-80 degrees C. (I) (esp. bromoacetylurea) are biocides (fungicides, nematocides, herbicides) for agricultural and horticultural use. The need for additional acid binding agents (e.g. amines or pyridine) is avoided. Simple washing with water and/or aq. NaHCO3 gives a product sufficiently pure for most purposes. Yield is ca 77-90%.</p>