ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9),申请号HR2016P000494T-传众专利搜索

ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9)

申请公布号：HRP20160494(T1)

申请号：HR2016P000494T

申请日期：2016.05.10

申请公布日期：2016.06.03

申请人：

Amgen Inc.

发明人：Jackson, Simon Mark;Walker, Nigel Pelham Clinton;Piper, Derek Evan;Shan, Bei;Shen, Wenyan;Chan, Joyce Chi Yee;King, Chadwick Terence;Ketchem, Randal Robert;Mehlin, Christopher;Carabeo, Teresa Arazas;Cao, Qiong

分类号：C07K16/40;A61K31/22;A61K31/366;A61K31/40;A61K31/405;A61K31/44;A61K31/47;A61K31/505;A61K31/66;A61K39/00;A61K39/395;A61K45/06;A61P3/06;C12N15/113

主分类号：C07K16/40

摘要：Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described.