IMIDAZO %1,2-B< ISOQUINOLINE DERIVATIVES

申请公布号：AU8628075(A)

申请号：AU19750086280

申请日期：1975.11.03

申请公布日期：1977.05.12

申请人：

ASPRO-NICHOLAS LTD.

发明人：RONALD FREDERICK COOKSON;DAVID PETER NOWOTNIK

分类号：C07C45/46;C07C45/63;C07C49/813;C07D271/10;C07D471/04

主分类号：C07C45/46

摘要：5,10-Dihydro-imidazo(1,2b)isoquinolines substituted in the 2- and/or 3-position(s) by an aromatic group have analgesic, anti-inflammatory or anti-pyretic activity. Except for 2-phenyl-5,10-dihydroimidazo(1,2b)isoquinoline, they are believed to be novel compounds. They can be prepared in manner known per se by heating a 2-acylmethyl isoquinolinium salt with an ammonium salt of an organic acid or by reaction of a 3-amino-1,4-dihydroisoquinoline with an alpha -halogenocarbonyl compound.

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