Stable drug form for oral administration with benzimidazole derivatives as active ingredient and process for the preparation thereof,申请号US20030665081-传众专利搜索

Stable drug form for oral administration with benzimidazole derivatives as active ingredient and process for the preparation thereof

申请公布号：US2005064035(A1)

申请号：US20030665081

申请日期：2003.09.16

申请公布日期：2005.03.24

发明人：HEESE GERD-ULFERT;JUNGER HERBERT;LAICHER ARNIM;LORCK CLAUDIO;PROFITLICH THOMAS;WEISS GERD

分类号：A61K9/32;A61K9/36;A61K9/50;A61K9/58;A61K9/62;A61K31/4439;(IPC1-7):A61K31/443;A61K9/24

主分类号：A61K9/32

摘要：The invention relates to a stable medicament for oral administration which comprises (a) a core which contains an active ingredient selected from Omeprazole, Lansoprazole and Pantoprazole, together with customary pharmaceutical adjuvants, (b) an intermediate layer applied onto the core, and (c) a gastric juice-resistant outer layer. The intermediate layer in (b) is formed as a reactive layer in which a gastric juice-resistant polymer layer material partially neutralized with alkali with cation exchange capacity is present. Further, a method for the production of the stable medicament is disclosed.