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Clavaspirins

申请公布号:AU6185898(A)

申请号:AU19980061858

申请日期:1998.02.26

申请公布日期:1998.09.18

申请人:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA,

发明人:ROBERT I LEHRER;IN-HEE LEE;CHENGQUAN ZHAO

分类号:A61K38/00;A61P43/00;C07K14/435;C12N15/12

主分类号:A61K38/00

摘要:Novel microbial peptides called clavaspirins are of the formula (SEQ ID NO:1)X'1X2B'3X4X5U6U7X8X9B10X'11X12U13B14X15X16B*17B18X19U20X21X'22X23(1)including the salts, esters, amides and acylated forms thereof wherein X is a hydrophobic amino acid residue or modified form thereof; X' is a small or a hydrophobic amino acid residue or a modified form thereof; B is a basic amino acid residue or modified form thereof; B' is basic or a polar/large amino acid residue or modified form thereof; B* is a basic or a hydrophobic amino acid residue or a modified form thereof; and U is a small amino acid residue or modified form thereof.

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