Chemoablation of tissue using biodegradable, solid salt dosage forms,申请号US20040940589-传众专利搜索

Chemoablation of tissue using biodegradable, solid salt dosage forms

申请公布号：US2005064046(A1)

申请号：US20040940589

申请日期：2004.09.14

申请公布日期：2005.03.24

申请人：

DITROLIO JOSEPH V.

发明人：DITROLIO JOSEPH V.

分类号：A61K33/14;A61M5/315;A61M31/00;A61M37/00;(IPC1-7):A61K33/14

主分类号：A61K33/14

摘要：Novel methods for the chemical ablation of tissue (e.g. prostatic tissue) are described. These methods include the steps of: (a) providing one or more solid salt dosage form comprising 50-100% w/w salt; and (b) inserting one or more of such solid salt dosage forms into the tissue. The solid salt dosage form is optionally inserted into the tissue under real-time ultrasonic observation. An advantage of the present invention is its ability to eliminate toxic byproducts. For example, where NaCl-based solid salt dosage forms are used to effect localized chemical ablation, the concentration is ultimately reduced to the level of normal saline (i.e., about 0.9%) upon absorption by the body of the subject being treated.